From route to lab process, CARBOGEN AMCIS optimizes the feasible route into a viable laboratory process. Depending on our clients’ need for support, we develop quantitative analytical methods for in-process controls, determine and optimize the critical parameters in the process, and optimize the work-up procedures.

Our goal: To develop a viable process for production at the pilot-plant scale, and provide the first multi-gram amounts of the target API.

At a minimum you can anticipate the following outcomes as a result of input combined with our activities:

Input

• Feasible route
• Qualitative analytic data (e.g. NMR, IR, UV, MS etc.)

Activities

• Evaluation of alternate conditions
• Stability testing
• Critical parameters determination (DOE)
• Work-up optimisation
• Analytical method development

Output

• Laboratory process
• Detailed report
• IPCs
• Quantitative analytical data (e.g. NMR, IR, UV, MS etc.)
• Samples and/or references
• Multi gram amounts