Chromatography Services#1094

Our Chromatography Services offer flexible and customized solutions for the separation and purification of lead compounds and intermediates. Our dedicated group of chromatographic specialists has cultivated expertise in method development, feasibility studies and scaling up chromatographic separations.

Depending on the method used, our typical scale ranges from 1 mg to 100 kg.

Purifications include:
APIs (cGMP), Intermediates, Starting Material, Impurities, Reference Standards, Metabolites

Our Chromatography Services also offer the added flexibility of integrating the separation step into a synthetic process for the manufacture of APIs for clinical and commercial use.

Services

Method Development:

  • Normal, reversed and chiral phase
  • Transfer of existing methods to preparative scale
  • Unbiased development of separations from scratch
  • Feasibility studies
  • Semi-preparative HPLC
  • Numerical simulations for SMB

Like all of our facilities, our chromatographic laboratories are equipped with cutting-edge equipment and a flexible infrastructure, which provide the capability to expand services rapidly to meet changing client needs.

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#1787
Case Study SMB

In the course of a recent project, a 11 step synthesis involved a late stage racemic intermediate, that required resolution into its   enantiomers.

#2185
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Center of Excellence: Chromatography Services

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